Excipients
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Excipients

Supporting formulation performance, stability, and manufacturability — Alfa Chemistry

Alfa Chemistry's pharmaceutical excipients product line brings a curated selection of high-quality excipients engineered to solve formulation challenges across oral, topical, parenteral, and specialty dosage forms. Need a highly compressible filler? Looking for solubility enhancers, controlled release modifiers or an excipient with improved patient acceptability? We can help speed development and ensure reproducible manufacturing with our excipient portfolio and technical support services.

What Are Pharmaceutical Excipients?

Excipients are the inactive ingredients in a drug product that support the active pharmaceutical ingredient (API): they act as fillers, binders, disintegrants, lubricants, coatings, solubilizers, stabilizers and more. Good excipient selection is key for drug stability, manufacturability, bioavailability and patient experience. Selecting the right excipients also significantly reduces development risk.

Explore Our Comprehensive Excipient Categories

Core Formulation Components

These excipients form the physical structure and base properties of the dosage form.

  • Fillers & Diluents: Add bulk to formulations for accurate dosage, e.g., microcrystalline cellulose, lactose.
  • Binders: Promote powder cohesion and granule formation for tablet integrity, e.g., povidone, starch.
  • Lubricants & Glidants: Ensure efficient tablet manufacturing by improving powder flow and preventing sticking, e.g., magnesium stearate, colloidal silicon dioxide.
  • Thickeners: Modify the viscosity of liquid and semi-solid formulations, e.g., hydroxyethyl cellulose, xanthan gum.

Stability and Performance Enhancers

This group is essential for maintaining drug efficacy and shelf-life.

  • Antioxidants: Prevent API degradation caused by oxidation.
  • Preservatives: Inhibit microbial growth in multi-dose and sterile formulations.
  • Chelating Agents: Enhance stability by sequestering metal ions that can catalyze degradation.
  • Stabilizers: A broad category of agents used to maintain the physical and chemical integrity of the formulation.
  • Buffers & pH Adjusters: Control and maintain the pH of the formulation to ensure stability and compatibility.

Solubility and Delivery Solutions

Advanced excipients critical for modern drug development, particularly for poorly soluble APIs and targeted delivery.

  • Surfactants & Emulsifiers: Enhance solubility and wetting, or create stable emulsions.
  • Solvents: Serve as the vehicle for liquid formulations.
  • Cyclodextrins: Form inclusion complexes to improve solubility and stability.
  • Phospholipids: Key components for liposomal and other advanced lipid-based delivery systems.
  • PEGylation Reagents: Used to conjugate with APIs to improve pharmacokinetics and reduce immunogenicity.
  • Drug Delivery Excipients: A specialized range of materials designed for controlled, targeted, or sustained release.

Patient-Centric Attributes

Excipients that improve the sensory experience and identification of the final product.

  • Sweeteners & Flavoring Agents: Mask unpleasant tastes and improve palatability, especially in oral liquids and chewable tablets.
  • Colorants: Provide product identification, brand differentiation, and aesthetic appeal.

Why Source Your Excipients from Alfa Chemistry?

Alfa Chemistry supplies excipients suitable for regulated drug products and offers comprehensive documentation to support regulatory submissions:

  • Pharmacopoeial grades (USP, EP, JP) where available.
  • Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS) for every batch.
  • Traceability across our supply chain and batch release records.
  • Manufacturing & packaging options aligned with required principles.
  • Support for stability testing and analytical method transfer upon request.

It should be noted that our service is only used for research, not for clinical use.

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