Ambrisentan
Ambrisentan
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Ambrisentan

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Catalog Number PR177036941
CAS 177036-94-1
Structure
Description Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension.
Synonyms Volibris
IUPAC Name (2S)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid
Molecular Weight 378.4
Molecular Formula C22H22N2O4
InChI InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)/t19-/m1/s1
InChI Key OUJTZYPIHDYQMC-LJQANCHMSA-N
Documentation/Certification CDMF
EC Number 658-059-9
Isomeric SMILES CC1=CC(=NC(=N1)O[C@H](C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)C
Standard In-house
Therapeutic Category Cardiovascular

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