Cemsidomide

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Cemsidomide

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Catalog Number	PR2504235678
CAS	2504235-67-8
Description	CFT7455 is a cereblon E3 ligase modulator with high affinity (Kd of 0.9 nM). CFT7455 acts as a molecular glue. It is an orally active zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3) degrader.
Synonyms	CFT7455
IUPAC Name	(3S)-3-[6-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-2-oxobenzo[cd]indol-1-yl]piperidine-2,6-dione
Molecular Weight	469.54
Molecular Formula	C28H27N3O4
Canonical SMILES	[H][C@@]1(CCC(=O)NC1=O)N1C(=O)C2=C3C1=CC=C(CC1=CC=C(CN4CCOCC4)C=C1)C3=CC=C2
InChI	InChI=1S/C28H27N3O4/c32-25-11-10-24(27(33)29-25)31-23-9-8-20(21-2-1-3-22(26(21)23)28(31)34)16-18-4-6-19(7-5-18)17-30-12-14-35-15-13-30/h1-9,24H,10-17H2,(H,29,32,33)/t24-/m0/s1
InChI Key	MUKCJOOKCZSQNW-DEOSSOPVSA-N
Purity	≥95%
Solubility	DMSO, DMF
Appearance	White solid
Shipping	Room temperature
Storage Conditions	Refrigerated

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