4-Cloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl)
4-Cloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl)
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4-Cloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl)

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Catalog NumberPR80841787-1

CAS Number80841-78-7

CategoryIntermediates

4-Cloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl)
Description 4-Chloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl), with CAS number 80841-78-7, serves a critical role in the pharmaceutical industry. It is primarily used as an intermediate in the synthesis of olmesartan medoxomil, an angiotensin II receptor antagonist. This makes it an essential reagent in the creation of medications aimed at managing high blood pressure. Additionally, DMDO-Cl is utilized in the preparation of prodrugs of ampicillin, further highlighting its versatility and importance in the development of therapeutic agents.
Synonyms 4-chloromethyl-5-methyl-2-oxo-1,3-dioxole;DMDO-CL;4-chloromethyl-5-methyl-1,3-dioxolen-2-one;
Molecular Weight 148.544
Molecular Formula C5H5ClO3
Boiling Point 163.2°C at 760 mmHg
Flash Point 66.7°C
Density 1.362g/cm3
Solubility Chloroform (Slightly), Methanol (Slightly).
Appearance Light-yellow to yellow liquid
Storage Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Assay ≥99.0%
Classification Heterocycles, Intermediates
EC Number 617-178-6
HS Code 2932999099
LogP 1.28
MDL Number MFCD07787494
PSA 43.35
Refractive Index 1.481
Vapor Pressure 2.1mmHg at 25°C

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