Elobixibat
Elobixibat
Contact Us

We are here to help in anything you need. Please use our online system or send an email to .

Elobixibat

Inquiry
Catalog Number PR439087180
CAS 439087-18-0
Description Elobixibat has been used in trials studying the treatment and basic science of Dyslipidemia, Constipation, Chronic Constipation, Functional Constipation, and Chronic Idiopathic Constipation.
IUPAC Name 2-[[(2R)-2-[[2-[(3,3-dibutyl-7-methylsulfanyl-1,1-dioxo-5-phenyl-2,4-dihydro-1lambda6,5-benzothiazepin-8-yl)oxy]acetyl]amino]-2-phenylacetyl]amino]acetic acid
Molecular Weight 695.9
Molecular Formula C36H45N3O7S2
InChI XFLQIRAKKLNXRQ-UUWRZZSWSA-N
InChI Key InChI=1S/C36H45N3O7S2/c1-4-6-18-36(19-7-5-2)24-39(27-16-12-9-13-17-27)28-20-30(47-3)29(21-31(28)48(44,45)25-36)46-23-32(40)38-34(26-14-10-8-11-15-26)35(43)37-22-33(41)42/h8-17,20-21,34H,4-7,18-19,22-25H2,1-3H3,(H,37,43)(H,38,40)(H,41,42)/t34-/m1/s1
Documentation/Certification Tech Pack
Drug Categories Alimentary Tract and Metabolism; Amino Acids, Peptides, and Proteins; Azepines; Drugs for Constipation; Oligopeptides; Peptides; Sulfur Compounds; Thiepins
Isomeric SMILES CCCCC1(CN(C2=CC(=C(C=C2S(=O)(=O)C1)OCC(=O)N[C@H](C3=CC=CC=C3)C(=O)NCC(=O)O)SC)C4=CC=CC=C4)CCCC
Standard ICH
Type Small Molecule
Therapeutic Category Irritable Bowel Syndrome
Pharmacology

Mechanism of Action

Elobixibat functions as a modulator of the ileal sodium/bile acid cotransporter in humans. By targeting this specific transport mechanism, Elobixibat effectively alters the reabsorption of bile acids within the ileum. This modulation leads to an increased flow of bile acids into the colon, which in turn stimulates colonic motility and enhances bowel function. Through this targeted action, Elobixibat offers a novel therapeutic approach for managing certain gastrointestinal conditions, providing an efficient means to regulate bowel movements and alleviate associated symptoms.

It should be noted that our service is only used for research, not for clinical use.