EN450

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EN450

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Catalog Number	PR793719014
CAS	793719-01-4
Description	EN450 is a cysteine-responsive covalent molecular gel degrader of targeted NF-κB with antiproliferative and potentially anticancer activity, which acts through a dependence on Cullin E3 ligase and protease, and can be used to study leukemia.
Synonyms	N-(2-Chloro-5-(N,N-dimethylsulfamoyl)phenyl)acrylamide
IUPAC Name	N-[2-chloro-5-(dimethylsulfamoyl)phenyl]prop-2-enamide
Molecular Weight	288.75
Molecular Formula	C11H13ClN2O3S
Canonical SMILES	O=C(C=C)NC1=CC(=CC=C1Cl)S(=O)(=O)N(C)C
InChI	InChI=1S/C11H13ClN2O3S/c1-4-11(15)13-10-7-8(5-6-9(10)12)18(16,17)14(2)3/h4-7H,1H2,2-3H3,(H,13,15)
InChI Key	OXFXDOLAQBMOPH-UHFFFAOYSA-N
Purity	>99.5%
Density	1.364 g/cm3 at 20 ℃ (Predicted)
Solubility	DMSO: 60 mg/mL (207.79 mM), Sonication is recommended.
Shipping	Shipping with blue ice.
Storage Conditions	Store at low temperatur

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