HB007

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HB007

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Catalog Number	PR2387821465
CAS	2387821-46-5
Description	HB007 is a small ubiquitin-related modifier 1 (SUMO1) degrader. HB007 induces ubiquitination and degradation of SUMO1, resulting in reduced tumor growth in vivo. HB007 can be used for the research of brain, breast, colon, and lung cancers.
Synonyms	1-(3-Chlorophenyl)-3-(6-cyano-1,3-benzothiazol-2-yl)urea
IUPAC Name	1-(3-chlorophenyl)-3-(6-cyano-1,3-benzothiazol-2-yl)urea
Molecular Weight	344.84
Molecular Formula	C15H9ClN4S2
Canonical SMILES	ClC1=CC(NC(=S)NC2=NC3=C(S2)C=C(C=C3)C#N)=CC=C1
InChI	InChI=1S/C15H9ClN4OS/c16-10-2-1-3-11(7-10)18-14(21)20-15-19-12-5-4-9(8-17)6-13(12)22-15/h1-7H,(H2,18,19,20,21)
InChI Key	URCZUKFRZQNQSQ-UHFFFAOYSA-N
Purity	≥95%
Solubility	DMSO, DMF
Appearance	White solid
Shipping	Room temperature
Storage Conditions	Refrigerated

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