LC3-mHTT-IN-AN1

LC3-mHTT-IN-AN1

Products

Contact Us

We are here to help in anything you need. Please use our online system or send an email to .

LC3-mHTT-IN-AN1

Inquiry

Catalog Number	PR486443736
CAS	486443-73-6
Description	Compound AN1 reduces mHTT levels through autophagic degradation by interacting with both the autophagosome protein microtubule-associated protein 1A/1B light chain 3 (LC3)1 and mutant huntingtin protein (mHTT). AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
Synonyms	LC3-mHTT-IN-1
IUPAC Name	(3Z)-5-bromo-3-[(3-bromo-4,5-dihydroxyphenyl)methylidene]-1H-indol-2-one
Molecular Weight	411.05
Molecular Formula	C15H9Br2NO3
Canonical SMILES	OC1=C(O)C(Br)=CC(\C=C2/C(=O)NC3=C2C=C(Br)C=C3)=C1
InChI	InChI=1S/C15H9Br2NO3/c16-8-1-2-12-9(6-8)10(15(21)18-12)3-7-4-11(17)14(20)13(19)5-7/h1-6,19-20H,(H,18,21)/b10-3-
InChI Key	GPKLWRHHVIBYEO-KMKOMSMNSA-N
Purity	≥95%
Solubility	DMSO, DMF
Appearance	White solid
Shipping	Room temperature
Storage Conditions	Refrigerated

It should be noted that our service is only used for research, not for clinical use.