Lenalidomide hydrochloride

Lenalidomide hydrochloride

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Lenalidomide hydrochloride

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Catalog Number	PR1243329976
CAS	1243329-97-6
Structure
Description	Lenalidomide hydrochloride (CC-5013 hydrochloride), a derivative of Thalidomide, acts as molecular glue. Lenalidomide hydrochloride is an orally active immunomodulator. Lenalidomide hydrochloride (CC-5013 hydrochloride) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hydrochloride (CC-5013 hydrochloride) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells.
Synonyms	CC-5013 hydrochloride
IUPAC Name	3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione;hydrochloride
Molecular Weight	295.72
Molecular Formula	C13H14ClN3O3
Canonical SMILES	O=C1C2=CC=CC(N)=C2CN1C(C(N3)=O)CCC3=O.[H]Cl
InChI	InChI=1S/C13H13N3O3.ClH/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18;/h1-3,10H,4-6,14H2,(H,15,17,18);1H
InChI Key	RYWZLJSDFZVVTD-UHFFFAOYSA-N
EC Number	815-073-1
Shipping	Generally, shipped at room temperature in continental US; may vary elsewhere.

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