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Losartan Potassium

Name: Losartan Potassium
SKU: PR124750998
Rating: 5 (1 reviews)

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Catalog NumberPR124750998

CAS Number124750-99-8

CategoryAntihypertensive

Description	Losartan Potassium is the potassium salt of losartan, a non-peptide angiotensin II receptor antagonist with antihypertensive activity. Losartan selectively and competitively binds to the angiotensin II receptor (type AT1) and blocks the binding of angiotensin II to the receptor, thus promoting vasodilatation and counteracting the effects of aldosterone.
Synonyms	Cozaar; Losacar; losartan potassium salt; Losaprex
IUPAC Name	potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,3-triaza-4-azanidacyclopenta-2,5-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
Molecular Weight	461.0
Molecular Formula	C22H22ClKN6O
InChI	OXCMYAYHXIHQOA-UHFFFAOYSA-N
InChI Key	InChI=1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
Isomeric SMILES	CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=N[N-]4)CO)Cl.[K+]
Therapeutic Category	Antihypertensive

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