Products

We are here to help in anything you need. Please use our online system or send an email to .

MRTX849 ethoxypropanoic acid

Name: MRTX849 ethoxypropanoic acid
SKU: PR2561529982
Rating: 5 (1 reviews)

Inquiry

Catalog NumberPR2561529982

CAS Number2561529-98-2

CategoryTarget Protein Ligand-Linker Conjugates

Description	MRTX849 ethoxypropanoic acid serves as a crucial component in advancing targeted cancer therapies by incorporating a ligand specific for the KRAS G12C mutation and a PROTAC linker. This combination is essential for the synthesis of PROTAC LC-2, which represents a pioneering approach in cancer treatment by effectively degrading endogenous KRAS G12C with an IC50 range between 0.25 and 0.76 μM, demonstrating its potency and specificity in targeting cancer cells.
Molecular Weight	720.23
Molecular Formula	C37H43ClFN7O5
Canonical SMILES	O=C(N1CCN(C2=C3CCN(CC3=NC(OC[C@@H]4CCCN4CCCOCCC(O)=O)=N2)C5=CC=CC6=C5C(Cl)=CC=C6)C[C@@H]1CC#N)C(F)=C
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Room temperature in continental US; may vary elsewhere.

It should be noted that our service is only used for research, not for clinical use.