NRX-1933

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NRX-1933

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Catalog Number	PR2763260304
CAS	2763260-30-4
Description	NRX-1933 is an enhancer of the interaction between beta-catenin and beta-TrCP. NRX-1933 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta-catenin by the 26S proteasome.
IUPAC Name	2-oxo-N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)-1H-pyridine-3-carboxamide
Molecular Weight	350.26
Molecular Formula	C14H9F3N6O2
Canonical SMILES	FC(F)(F)C1=CC=C(C(=O)NC2=CC(=CC=C2)C2=NN=NN2)C(=O)N1
InChI	InChI=1S/C14H9F3N6O2/c15-14(16,17)10-5-4-9(13(25)19-10)12(24)18-8-3-1-2-7(6-8)11-20-22-23-21-11/h1-6H,(H,18,24)(H,19,25)(H,20,21,22,23)
InChI Key	IAVMZDPIQIVLOG-UHFFFAOYSA-N
Purity	≥95%
Solubility	DMSO, DMF
Appearance	White solid
Shipping	Room temperature
Storage Conditions	Refrigerated

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