NRX-103095

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NRX-103095

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Catalog Number	PR2763260382
CAS	2763260-38-2
Description	NRX-103095 is an enhancer of the interaction between beta-catenin and beta-TrCP. NRX-103095 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta-catenin by the 26S proteasome.
IUPAC Name	4-(2,6-dichlorophenyl)sulfanyl-N-[3-(dimethylcarbamoyl)phenyl]-2-oxo-6-(trifluoromethyl)-1H-pyridine-3-carboxamide
Molecular Weight	530.34
Molecular Formula	C22H16Cl2F3N3O3S
Canonical SMILES	CN(C)C(=O)C1=CC=CC(NC(=O)C2=C(SC3=C(Cl)C=CC=C3Cl)C=C(NC2=O)C(F)(F)F)=C1
InChI	InChI=1S/C22H16Cl2F3N3O3S/c1-30(2)21(33)11-5-3-6-12(9-11)28-19(31)17-15(10-16(22(25,26)27)29-20(17)32)34-18-13(23)7-4-8-14(18)24/h3-10H,1-2H3,(H,28,31)(H,29,32)
InChI Key	BGEHEUAOZPAMKC-UHFFFAOYSA-N
Purity	≥95%
Solubility	DMSO, DMF
Appearance	White solid
Shipping	Room temperature
Storage Conditions	Refrigerated

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