Poloxamer 407
Poloxamer 407
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Poloxamer 407

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Catalog NumberPR9003116-1

CAS Number9003-11-6

CategorySurfactants & Emulsifiers

Poloxamer 407
Description Poloxamer 407 is a versatile pharmaceutical excipient widely used for its surfactant, emulsifying, and solubilizing properties. It is a block copolymer of polyethylene oxide and polypropylene oxide, making it highly effective in stabilizing formulations and enhancing the bioavailability of poorly soluble drugs. Poloxamer 407 can gel upon temperature change, which is particularly useful for creating thermoreversible gels used in drug delivery systems such as topical, ophthalmic, or injectable formulations. Its ability to form micelles also aids in encapsulating and delivering hydrophobic compounds. Moreover, it is considered biologically inert and safe, which makes it an attractive option for various pharmaceutical applications including controlled-release formulations and protein stabilization.
Synonyms Pluronic F127; Polyethylene-Polypropylene Glycol
Molecular Formula HO(C2H4O)a(C3H6O)b(C2H4O)aH
Grade NF

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