Tromethamine
Tromethamine
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Tromethamine

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Catalog NumberPR77861-1

CAS Number77-86-1

CategorySurfactants & Emulsifiers

Tromethamine
Description Tromethamine, also known as Tris, is widely used as a pharmaceutical excipient primarily due to its buffering capacity and ability to stabilize formulations. Serving as a pH adjuster, it helps maintain the stability and solubility of drugs, ensuring optimal bioavailability and efficacy. Tromethamine is particularly valuable in injectable and ophthalmic solutions, where precise pH control is crucial to prevent irritation or degradation of active pharmaceutical ingredients. Its compatibility with both acidic and basic drugs enhances its versatility across diverse formulations. Additionally, tromethamine acts as an emulsifying agent and is often included to improve the solubility of lipophilic drugs, facilitating their effective delivery. Its low toxicity and pharmacological inertness further underscore its suitability as a reliable excipient in various pharmaceutical applications.
Synonyms Tromethamine; Trismat; Trometamol; TRIS; TRIS Base
Molecular Formula C4H11NO3
Grade USP

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